REVERCHON E.

Liposomes are created when phospholipids self-assemble in an aqueous medium creating spherical closed structures. These vesicles can be loaded with hydrophilic active principles (AP) into the aqueous inner core or with lipophilic compounds in the lipidic double layer. In this work a new supercritical based process for the one-step continuous...

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Liposomes are spherical vesicles made up of an aqueous core surrounded by phospholipids. These delivery systems (DS) are largely employed as drug carriers in several industrial fields, such as pharmaceutical and nutraceutical fields. The aim of this short review is to provide a fast overview on the main fundamentals of liposomes, thought as a...

Two different strategies for the encapsulation of hydrophobic bioactives within nanoliposomes were attempted. Three model lipophilic antioxidants (farnesol, limonene, linalool) were entrapped in liposomes using emulsions: drug was dissolved in the oil phase of an oil in water emulsion; then, the aqueous emulsion was entrapped in liposomes inner...

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In this work, the precipitation of a model compound (cefonicid) from DMSO by Supercritical Antisolvent (SAS) was performed. Various morphologies; i.e., expanded microparticles, microparticles, and nanoparticles were obtained, varying operating conditions. In order to explain these results, high-pressure vapor-liquid phase equilibria (VLEs) of...

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