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RICCI , Vittorio

Last name: RICCI

First name: Vittorio

2017 (v1)

Publication

Metadata-only

Natural history of Helicobacter pylori VacA toxin in human gastric epithelium in vivo: Vacuoles and beyond

Necchi, Vittorio Sommi, Patrizia Vanoli, Alessandro

Uptake, intracellular trafficking and pathologic effects of VacA toxin from Helicobacter pylori have been widely investigated in vitro. However, no systematic analysis investigated VacA intracellular distribution and fate in H. pylori-infected human gastric epithelium in vivo, using ultrastructural immunocytochemistry that combines precise...

Uploaded on: April 14, 2023
March 5, 2004 (v1)

Journal article

Metadata-only

Glycosylphosphatidylinositol-anchored proteins and actin cytoskeleton modulate chloride transport by channels formed by the Helicobacter pylori vacuolating cytotoxin VacA in HeLa cells.

Gauthier, Nils C Ricci, Vittorio Gounon, Pierre

The vacuolating cytotoxin VacA is an important virulence factor of Helicobacter pylori. Removing glycosylphosphatidylinositol-anchored proteins (GPI-Ps) from the cell surface by phosphatidylinositol-phospholipase C or disrupting the cell actin cytoskeleton by cytochalasin D reduced VacA-induced vacuolation of cells. Using the fluorescent dye...

Uploaded on: December 4, 2022