May 22, 2023 (v1)
Publication
Regulatory T cells (Tregs) are modulators of the immune system that play a key role in maintaining self-tolerance. Treg were initially identified by Sakaguchi as CD4+CD25+ T cells that have the ability to suppress autoimmune responses. They were further shown to rely on the expression of the transcription factor FOXP3, whose loss leads to a...
Uploaded on: May 24, 2023