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2020 (v1)PublicationUploaded on: April 14, 2023
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2020 (v1)Publication
PURPOSE OF REVIEW: The aim of this review is to provide an update on the pathophysiology and treatment of severe traumatic brain injury (TBI)-related complications on extracranial organs. RECENT FINDINGS: Extracranial complications are common and influence the outcome from TBI. Significant improvements in outcome in a sizeable proportion of...
Uploaded on: April 14, 2023 -
2020 (v1)Publication
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Uploaded on: April 14, 2023 -
2019 (v1)Publication
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Uploaded on: April 14, 2023 -
2020 (v1)Publication
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Uploaded on: April 14, 2023 -
2021 (v1)Publication
No abstract present.
Uploaded on: April 14, 2023 -
2020 (v1)Publication
The microbiota–gut–brain axis is considered a central regulator of the immune system after acute ischemic stroke (AIS), with a potential role in determining outcome. Several pathways are involved in the evolution of gut microbiota dysbiosis after AIS. Brain–gut and gut–brain signaling pathways involve bidirectional communication between the...
Uploaded on: April 14, 2023 -
2021 (v1)Publication
Aneurysmal subarachnoid hemorrhage (aSAH) results from the rupture of an intracranial aneurysm and represents a highly debilitating and devastating disorder. The prevalence rate of neuroendocrine impairment in the acute phase is extremely variable, ranging from 3.8% to 92.3%, depending on the time point considered, the method/test utilized, the...
Uploaded on: April 14, 2023 -
2020 (v1)Publication
Purpose of review The widespread diffusion of extended-spectrum β-lactamases (ESBLs)-producing Enterobacteriales currently represents a major threat for public health worldwide. Carbapenems are currently considered the first-line choice for serious ESBL infections. However, the dramatic global increase in ESBL prevalence has led to a...
Uploaded on: March 27, 2023 -
2019 (v1)Publication
The acute respiratory distress syndrome (ARDS) is a multifaceted lung disorder in which no specific therapeutic intervention is able to effectively improve clinical outcomes. Despite an improved understanding of molecular mechanisms and advances in supportive care strategies, ARDS remains associated with high mortality, and survivors usually...
Uploaded on: April 14, 2023 -
2020 (v1)Publication
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Uploaded on: April 14, 2023 -
2019 (v1)Publication
Most patients with ischaemic stroke are managed on the ward or in specialty stroke units, but a significant number requires higher-acuity care and, consequently, admission to the intensive care unit. Mechanical ventilation is frequently performed in these patients due to swallowing dysfunction and airway or respiratory system compromise....
Uploaded on: April 14, 2023 -
2022 (v1)Publication
Introduction: The coronavirus disease 2019 (COVID-19) pandemic has put a strain on global healthcare systems. Despite admirable efforts to develop rapidly new pharmacotherapies, supportive treatments remain the standard of care. Multiple clinical trials have failed due to design issues, biased patient enrollment, small sample sizes, inadequate...
Uploaded on: July 10, 2024 -
2019 (v1)Publication
Background: This pilot study was designed to develop a fully automatic and quantitative scoring system of B-lines (QLUSS: quantitative lung ultrasound score) involving the pleural line and to compare it with previously described semi-quantitative scores in the measurement of extravascular lung water as determined by standard thermo-dilution....
Uploaded on: April 14, 2023 -
2020 (v1)Publication
Background: Severe traumatic brain injury (TBI) patients often develop acute respiratory failure. Optimal ventilator strategies in this setting are not well established. We performed an international survey to investigate the practice in the ventilatory management of TBI patients with and without respiratory failure. Methods: An electronic...
Uploaded on: March 27, 2023