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ROBLES FRÍAS , María José

Last name: ROBLES FRÍAS

First name: María José

October 10, 2022 (v1)

Publication

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Delayed administration of ixazomib modifies the immune response and prevents chronic graft-versus-host disease

Ramos, Teresa L. García Guerrero, Estefanía Caballero Velázquez, Teresa

In this study, we aimed to modify the immune response in the long term after allogeneic bone marrow transplantation (allo-BMT) by using the proteasome inhibitor ixazomib (IXZ) at the late stages of the post-transplant period. This approach facilitated the immune reconstitution after transplantation. IXZ significantly prolonged survival and...

Uploaded on: December 4, 2022
June 8, 2022 (v1)

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Selective inhibition of HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma

García Domínguez, Daniel Hajji, Nabil Sánchez Molina, Sara

Ewing sarcoma (EWS) is an aggressive bone and soft tissue tumor of children and young adults in which the principal driver is a fusion gene, EWSR1-FLI1. Although the essential role of EWSR1-FLI1 protein in the regulation of oncogenesis, survival, and tumor progression processes has been described in-depth, little is known about the regulation...

Uploaded on: March 25, 2023