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Last name: RODRÍGUEZ REAL
First name: Guillermo
Los centrosomas funcionan como los centros organizadores de microtubulos principales en la mayoría de las células animales. Cambios en la estructura o el número de este orgánulo están asociados con errores de segregación ...
The repair of DNA breaks takes place in the context of chromatin and thus involves the activity of chromatin remodelers. The nucleosome acetyltransferase of H4 (NuA4) remodeler complex enables DNA break repair by relaxing flanking chromatin. Here, we show that MRG domain binding protein (MRGBP), a member of this complex, acts as a general...
In order to survive to the exposure of DNA damaging agents, cells activate a complex response that coordinates the cellular metabolism, cell cycle progression, and DNA repair. Among many other events, recent evidence has described global changes in mRNA splicing in cells treated with genotoxic agents. Here, we explore further this DNA...