RODRIGO HERRERO , Silvia

INTRODUCTION Alzheimer's disease (AD) is the most frequent cause of dementia (60-80%). Loss of binding and difficulties in encoding new information are early signs of hippocampal dysfunction and may facilitate an early AD diagnosis, a challenge for clinicians who evaluate patients with memory complaints. To detect hippocampal dysfunction, we...

Brain aquaporin 1 (AQP1) and AQP4 are involved in cerebrospinal fluid (CSF) homeostasis and might participate in the origin of hydrocephalus. Studies have shown alterations of perivascular AQP4 expression in idiopathic normal pressure hydrocephalus (iNPH) and Alzheimer's disease (AD). Due to the overlapping of clinical signs between iNPH and...