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ROLLI-DERKINDEREN , Malvyne

Last name: ROLLI-DERKINDEREN

First name: Malvyne

2005 (v1)

Journal article

Metadata-only

Phosphorylation of serine 188 protects RhoA from ubiquitin/proteasome-mediated degradation in vascular smooth muscle cells.

Rolli-Derkinderen, Malvyne Sauzeau, Vincent Boyer, Laurent

cAMP and cyclic GMP-dependent kinases (PKA and PKG) phosphorylate the small G protein RhoA on Ser188. We have previously demonstrated that phosphorylation of Ser188 inhibits RhoA-dependent functions and positively regulates RhoA expression, and that the nitric oxide (NO)/cGMP-dependent protein kinase pathway plays an essential role, both in...

Uploaded on: December 4, 2022