El agrandamiento gingival es una entidad patológica englobada dentro de la clasificación de la enfermedad periodontal. Las causas más comunes son en primer lugar como manifestación secundaria al consumo de fármacos - hidantoínas, ciclosporina y bloqueantes de los canales del calcio – y en segundo lugar, la forma idiopática asociada a un...
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September 28, 2016 (v1)PublicationUploaded on: December 4, 2022
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September 26, 2017 (v1)Publication
Periodontal disease is considered one of the main pathologic diseases occurring in humans. Its pathologic process involves inflammatory reactions producing periodontal bone resorption and the tooth loss. But some patients do not present an evident clinical inflammation with bone resorption, and in others, the inflammation is prominent without...
Uploaded on: March 27, 2023 -
September 6, 2019 (v1)Publication
Hereditary gingival fibromatosis is a disorder for which the etiology remains unknown. We aimed to evaluate the fibroblasts and histological alterations to give new clues. A father and a daughter of a family showing gingival hereditary fibromatosis were treated, and gingival biopsies were obtained. A histological study revealed dense fibrous...
Uploaded on: March 1, 2023 -
January 24, 2019 (v1)Publication
Impairment in adenosine monophosphate-activated protein kinase (AMPK) activity and NOD-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome activation are associated with several metabolic and inflammatory diseases. In this study, we investigated the role of AMPK/NLRP3 inflammasome axis in the molecular mechanism underlying pain...
Uploaded on: December 4, 2022 -
March 17, 2017 (v1)PublicationCould NLRP3–inflammasome be a cardiovascular risk biomarker in acute myocardial infarction patients?
Conventional cardiovascular risk factors (CVRFs) are accepted to identify asymptomatic individuals with high risk of acute myocardial infarction (AMI). However, AMI affects many patients previously classified at low risk. New biomarkers are needed to improve risk prediction. We propose to evaluate the NLRP3–inflammasome complex as a potential...
Uploaded on: March 27, 2023