We conducted a randomized controlled trial to examine choral singing's effect on cognitive decline in aging. Older Singaporeans who were at high risk of future dementia were recruited: 47 were assigned to choral singing intervention (CSI) and 46 were assigned to health education program (HEP). Participants attended weekly one-hour choral...
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May 4, 2023 (v1)PublicationUploaded on: May 5, 2023
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October 10, 2023 (v1)Publication
BACKGROUND: A plethora of cutting-edge neuroimaging analyses have been developed and published, yet they have not hitherto been realized as improvements in neurosurgical outcomes. In this paper we propose a novel interface be- tween neuroimaging and neurosurgery for aiding translational research. Our objective is to create a method for applying...
Uploaded on: October 13, 2023 -
September 28, 2022 (v1)Publication
Understanding the cellular underpinnings of neurodegeneration remains a challenge; loss of synapses and dendritic arborization are characteristic and can be quantified in vivo, with [11C]UCB-J PET and MRI-based Orientation Dispersion Imaging (ODI), respectively. We aimed to assess how both measures are correlated, in 4R-tauopathies of...
Uploaded on: March 24, 2023 -
October 20, 2022 (v1)Publication
Predicting functional outcomes after surgery and early adjuvant treatment is difficult due to the complex, extended, interlocking brain networks that underpin cognition. The aim of this study was to test glioma functional interactions with the rest of the brain, thereby identifying the risk factors of cognitive recovery or deterioration....
Uploaded on: March 24, 2023 -
September 28, 2022 (v1)Publication
Essential tremor (ET) is a highly prevalent neurological disorder characterized by action- induced tremors involving the hand, voice, head, and/or face. Importantly, hand tremor is present in nearly all forms of ET, resulting in impaired fine motor skills and diminished quality of life. To advance early diagnostic approaches for ET, automated...
Uploaded on: March 24, 2023