Dentro de este marco general y como consecuencia de una colaboración establecida con BayerCropScience GmbH, en esta Tesis Doctoral se han desarrollado nuevas metodologías de síntesis específicamente dirigidas a la obtención de familias de productos con especial relevancia como intermedios para la síntesis de herbicidas de última generación. L...
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October 10, 2016 (v1)PublicationUploaded on: December 4, 2022
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January 9, 2018 (v1)Publication
The direct borylation of hydrocarbons via C-H activation has reached an impressive level of sophistication and efficiency, emerging as a fundamental tool in synthesis because of the versatility offered by organoboron compounds. As a remarkable particularity, the catalytic systems originally developed for these reactions are relatively...
Uploaded on: March 27, 2023 -
January 21, 2020 (v1)Publication
Four new dyes that derive from borylated arylisoquinolines were prepared, containing a third aryl residue (naphthyl, 4-methoxynaphthyl, pyrenyl or anthryl) that is linked via an additional stereogenic axis. The triaryl cores were synthesized by Suzuki couplings and then transformed into boronic acid esters by employing an Ir(I)-catalyzed...
Uploaded on: December 5, 2022 -
February 19, 2018 (v1)Publication
The 1,3-dipolar cycloaddition of a variety of aromatic and aliphatic nitrile oxides to 2,5-trans-2,5-diphenylpyrrolidine derived acrylamide and cinnamamide efficiently affords the corresponding 4,5-dihydroisoxazole-5- carboxamides in a highly regio- and stereoselective manner. The cycloaddition of aliphatic nitrile oxides to the analogue...
Uploaded on: December 4, 2022 -
November 3, 2022 (v1)Publication
A series of chiral platina[5]helicenes displaying dual luminescence, i.e., fluorescence between 450 and 600 nm and red/NIR phosphorescence between 700 and 900 nm, has been synthesised, characterised and studied by first-principle calculations. This unusual behavior has been attributed to limited electronic interactions between the d orbitals of...
Uploaded on: March 24, 2023 -
February 1, 2019 (v1)Publication
Adiastereo- and highly enantioselective dynamic kinetic resolution (DKR) of configurationally labile hetero- biaryl ketones is described. The DKR proceeds by zinc- catalyze dhydrosilylation of the carbonyl group ,thus leading to secondary alcohols bearing axial and central chirality .The strategy relies on the labilization of the...
Uploaded on: March 27, 2023 -
November 3, 2022 (v1)Publication
Conveniently modified polycyclic aromatic hydrocarbon (PAH) fluorophores are obtained by a bromination–borylation sequence. The bis-borylated dyes show red-shifted absorption (λabs,max > 450 nm) and emission (λf,max > 500 nm; Φf: 0.3–0.5) properties as compared to the parent PAHs. Their centrosymmetric A–π-A (A: acceptor) structures led to the...
Uploaded on: March 24, 2023 -
February 1, 2019 (v1)Publication
A highly diastereo- and enantioselective, scalable Pd-catalyzed dynamic kinetic asymmetric Heck reaction of heterobiaryl sulfonates with electron-rich olefins is described. The coupling of 2,3-dihydrofuran or N-boc protected 2,3-dihydropyrrole with a variety of quinoline, quinazoline, phthalazine, and picoline derivatives takes place with...
Uploaded on: December 4, 2022 -
November 10, 2022 (v1)Publication
Six strongly fluorescent four-coordinate organoboron N,C chelates containing an aryl isoquinoline skeleton were prepared. Remarkably, the fluorescence quantum yields reach values of up to 0.74 in oxygen-free toluene. The strong B-N interaction was corroborated by the single-crystal X-ray analysis of two dyes. The intramolecular charge-transfer...
Uploaded on: December 5, 2022