Background: Juvenile idiopathic arthritis (JIA) is characterized by synovial inflammation, with potential risk of developing progressive joint destruction. Personalized state-of-the-art treatment depends on valid markers for disease activity to monitor response; however, no such markers exist. Objective: To evaluate the reliability of scoring...
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2015 (v1)PublicationUploaded on: April 14, 2023
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2018 (v1)Publication
Background: Approximately 20–50% of children with juvenile idiopathic arthritis (JIA) have hip involvement within 6 years of diagnosis. Scoring systems for hip-related radiographic changes are lacking. Objective: To examine precision of potential radiographic variables and to suggest a scoring system. Materials and methods: We reviewed a set of...
Uploaded on: April 14, 2023 -
2018 (v1)Publication
Wrist involvement occurs in about one-quarter of patients diagnosed with juvenile idiopathic arthritis (JIA), increasing to 40% 5 years after diagnosis. The imaging appearances, both for active inflammation and permanent change, differ from those seen in adult rheumatoid arthritis; therefore, a child-specific approach is crucial for correct...
Uploaded on: April 14, 2023 -
2018 (v1)Publication
Objective. To extend the magnetic resonance imaging (MRI) score for assessment of wrist synovitis in juvenile idiopathic arthritis (JIA) by inclusion of the metacarpophalangeal (MCP) joints, and to compare the metric properties of the original and the extended score. Methods. Wrist MRI of 70 patients with JIA were scored by 3 independent...
Uploaded on: April 14, 2023 -
2016 (v1)Publication
To report on the progress of an ongoing research collaboration on magnetic resonance imaging (MRI) in juvenile idiopathic arthritis (JIA) and describe the proceedings of a meeting, held prior to Outcome Measures in Rheumatology (OMERACT) 12, bringing together the OMERACT MRI in JIA working group and the Health-e-Child radiology group. The goal...
Uploaded on: March 27, 2023 -
2023 (v1)Publication
Background Hip involvement predicts severe disease in juvenile idiopathic arthritis (JIA) and is accurately assessed by MRI. However, a child-specific hip MRI scoring system has not been validated.Objective To test the intra- and interobserver agreement of several MRI markers for active and chronic hip changes in children and young adults with...
Uploaded on: February 14, 2024 -
2016 (v1)Publication
Background: Potential long-term side effects of treatment for juvenile idiopathic arthritis are concerning. This has necessitated accurate tools, such as MRI, to monitor treatment response and allow for personalized therapy. Objective: To examine the extent to which timing of post-contrast MR images influences the scoring of inflammatory change...
Uploaded on: April 14, 2023 -
2018 (v1)Publication
Imaging is increasingly being integrated into clinical practice to improve diagnosis, disease control and outcome in children with juvenile idiopathic arthritis. Over the last decades several international groups have been launched to standardize and validate different imaging techniques. To enhance transparency and facilitate collaboration, we...
Uploaded on: April 14, 2023