Tissues must adapt to the different external stimuli so that organisms can survive in their environments. The intestine is a vital organ involved in food processing and absorption, as well as in innate immune response. Its adaptation to environmental cues such as diet and biotic/abiotic stress involves regulation of the proliferative rate and a...
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September 2020 (v1)Journal articleUploaded on: December 4, 2022
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2003 (v1)Journal article
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Uploaded on: December 4, 2022 -
April 2017 (v1)Journal article
Highlights d JNK controls Mixer cell reprogramming through Polycomb downregulation d HOX genes spatially regulate cell mixing at segment boundaries d Abdominal-A acts as a pro-mixing factor d Abdominal-B is a prevalent, negative regulator of cell mixing
Uploaded on: December 4, 2022 -
May 8, 2009 (v1)Journal article
JNK-mediated closure of the Drosophila dorsal epidermis during embryogenesis is a well-characterised model for morphogenesis. However, little is known about how JNK signalling modifies particular cellular behaviours such as intracellular transport. Here we demonstrate that the gene encoding the small GTPase Rab30 is a new JNK transcriptional...
Uploaded on: December 3, 2022 -
June 17, 2003 (v1)Journal article
Recent quantitative modeling of dorsal closure in the fruitfly Drosophila has revealed how multiple forces drive sealing of the two symmetrical epithelial sheets. A predictive model based on the new data allows gene function to be linked to the forces that drive tissue movement.
Uploaded on: December 4, 2022 -
October 2020 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
April 13, 2023 (v1)Publication
3rd cycle
Uploaded on: October 11, 2023 -
February 23, 2017 (v1)Journal article
Tissue morphogenesis relies on proper differentiation of morphogenetic domains, adopting specific cell behaviours. Yet, how signalling pathways interact to determine and coordinate these domains remains poorly understood. Dorsal closure (DC) of the Drosophila embryo represents a powerful model to study epithelial cell sheet sealing. In this...
Uploaded on: December 4, 2022 -
2010 (v1)Journal article
Segments are fundamental units in animal development which are made of distinct cell lineages separated by boundaries. Although boundaries show limited plasticity during their formation for sharpening, cell lineages make compartments that become tightly restricted as development goes on. Here, we characterize a unique case of breaking of the...
Uploaded on: December 4, 2022 -
July 2010 (v1)Journal article
In Drosophila melanogaster, dorsal closure is a model of tissue morphogenesis leading to the dorsal migration and sealing of the embryonic ectoderm. The activation of the JNK signal transduction pathway, specifically in the leading edge cells, is essential to this process. In a genome-wide microarray screen, we identified new JNK target genes...
Uploaded on: December 3, 2022 -
October 20, 2022 (v1)Publication
Bacillus thuringiensis subsp. kurstaki (Btk) is a strong pathogen toward lepidopteran larvae thanks to specific Cry toxins causing leaky gut phenotypes. Hence, Btk and its toxins are used worldwide as microbial insecticide and in genetically modified crops, respectively, to fight crop pests. However, Btk belongs to the B. cereus group, some...
Uploaded on: December 4, 2022 -
January 19, 2024 (v1)Journal article
International audience
Uploaded on: January 22, 2024 -
September 4, 2024 (v1)Journal article
Strains of the Bacillus cereus (Bc) group are sporulating bacteria commonlyassociated with foodborne outbreaks. Spores are dormant cells highly resistantto extreme conditions. Nevertheless, the pathological processes associatedwith the ingestion of either vegetative cells or spores remain poorlyunderstood. Here, we demonstrate that while...
Uploaded on: September 14, 2024 -
September 4, 2024 (v1)Journal article
Strains of the Bacillus cereus (Bc) group are sporulating bacteria commonly associated with foodborne outbreaks. Spores are dormant cells highly resistant to extreme conditions. Nevertheless, the pathological processes associated with the ingestion of either vegetative cells or spores remain poorly understood. Here, we demonstrate that while...
Uploaded on: September 9, 2024