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RUÍZ BORREGO , Manuel

Last name: RUÍZ BORREGO

First name: Manuel

March 17, 2017 (v1)

Publication

Metadata-only

Prognostic value of CtIP/RBBP8 expression in breast cancer

Soria Bretones, Isabel Ruíz Borrego, Manuel Japón Rodríguez, Miguel Ángel

CtIP/RBBP8 is a multifunctional protein involved in transcription, DNA replication, DNA repair by homologous recombination and the G1 and G2 checkpoints. Its multiple roles are controlled by its interaction with several specific factors, including the tumor suppressor proteins BRCA1 and retinoblastoma. Both its functions and interactors point...

Uploaded on: December 4, 2022
October 9, 2020 (v1)

Publication

Metadata-only

EDIL3 promotes epithelial–mesenchymal transition and paclitaxel resistance through its interaction with integrin αVβ3 in cancer cells

Gasca, Jessica Flores, María Luz Jiménez Guerrero, Rocío

Epithelial–mesenchymal transition (EMT) has recently been associated with tumor progression, metastasis, and chemotherapy resistance in several tumor types. We performed a differential gene expression analysis comparing paclitaxel-resistant vs. paclitaxel-sensitive breast cancer cells that showed the upregulation of EDIL3 (EGF Like Repeats and...

Uploaded on: March 26, 2023