RUGGIERI , Filippo Grillo

Colorectal cancer patients' responses to neoadjuvant therapy undergo broad inter-individual variations. The aim of this systematic review is to identify a molecular signature that is predictive of colon cancer downstaging and/or downgrading after neoadjuvant therapy. Among the hundreds analysed in the available studies, only 19 messenger-RNAs...

Monte Carlo simulation for external beam radiotherapy requires precise modeling of the treatment linear accelerator head and of the primary electron beam. Detailed modeling of medical accelerators is complex and could require proprietary data, and the production of an adequate sample of primary particles to simulate statistically significant...