La pancreastatina, un péptido de 49 aminoacidos, fue Aislada del páncreas porcino en diciembre de 1986, se Encuentra distribuida por todo el sistema neuroendocrino Y tiene como posible precursor a la cromogranina a. Se le Ha dado un papel autorregulador de la célula beta, Inhibiendo la secreción de insulina con la que se Cosecreta. En esta...
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September 6, 2016 (v1)PublicationUploaded on: March 27, 2023
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September 24, 2018 (v1)Publication
The STAR family of proteins links signaling pathways to various aspects of post-transcriptional regulation and processing of RNAs. Sam68 belongs to this class of heteronuclear ribonucleoprotein particle K (hnRNP K) homology (KH) single domain-containing family of RNA-binding proteins that also contains some domains predicted to bind critical...
Uploaded on: December 4, 2022 -
December 17, 2014 (v1)Publication
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Uploaded on: December 4, 2022 -
September 30, 2020 (v1)Publication
Inflammation is an essential immune response for the maintenance of tissue homeostasis. In a general sense, acute and chronic inflammation are different types of adaptive response that are called into action when other homeostatic mechanisms are insufficient. Although considerable progress has been made in understanding the cellular and...
Uploaded on: December 5, 2022 -
April 26, 2019 (v1)Publication
Se estudió el efecto de la fecha de siembra de L. a/bus cv. Multolupa sobre el crecimiento, producción y componentes de la producción, en cultivo de secano, en la provincia de Sevilla, durante tres años. El retraso en la siembra provocó una reducción en la producción de paja y de grano, pero no se encontraron diferencias significativas en...
Uploaded on: March 27, 2023 -
May 27, 2021 (v1)Publication
Obesity-related breast cancer is an important threat that affects especially post-menopausal women. The link between obesity and breast cancer seems to be relying on the microenvironment generated at adipose tissue level, which includes inflammatory cytokines. In addition, its association with systemic endocrine changes, including...
Uploaded on: March 24, 2023 -
June 7, 2023 (v1)Publication
It is widely accepted that the immune system includes molecular and cellular components that play a role in regulating and suppressing the effector immune response in almost any process in which the immune system is involved. Myeloid-derived suppressor cells (MDSCs) are described as a heterogeneous population of myeloid origin, immature state,...
Uploaded on: June 9, 2023 -
February 5, 2024 (v1)Publication
Background: Physiological changes during pregnancy, such as dilutional anemia and a reduced half-life of red blood cells, have prevented the use of glycated Hb (HbA1c) as a biomarker for gestational diabetes mellitus (GDM). Nevertheless, increasing evidence supports the use of HbA1c in GDM diagnostic strategies.We studied HbA1c as a biomarker...
Uploaded on: February 7, 2024 -
April 21, 2023 (v1)Publication
Background and objective: Polycystic ovary syndrome (PCOS) is a complex metabolic disorder associated with ovulatory dysfunction, hyperandrogenism, obesity, and insulin resistance, which leads to subfertility. PCOS is the most frequent metabolic disorder in women and the major cause of infertility. Susceptibility to developing PCOS is...
Uploaded on: April 23, 2023 -
June 12, 2023 (v1)Publication
Introduction: Polycystic ovary syndrome (PCOS) is a complex metabolic disorder associated with ovulatory dysfunction, hyperandrogenism, obesity, and insulin resistance, that leads to subfertility. Sam68 is an RNA-binding protein with signaling functions that is ubiquitously expressed, including gonads. Sam68 is recruited to leptin signaling,...
Uploaded on: June 14, 2023 -
May 20, 2021 (v1)Publication
Leptin is highly expressed in the placenta, mainly by trophoblastic cells, where it has an important autocrine trophic effect. Moreover, increased leptin levels are found in the most frequent pathology of pregnancy: gestational diabetes, where leptin may mediate the increased size of the placenta and the fetus, which becomes macrosomic. In...
Uploaded on: March 25, 2023