SÁNCHEZ MARTÍN , Pascual

El objetivo de esta Tesis Doctoral es determinar qué estrategias muestran mayor eficacia para seleccionar en una muestra seminal al espermatozoide más adecuado que permita el éxito clínico en los tratamientos de reproducción asistida en parejas estériles por un factor masculino. De este modo se pretende que la evidencia empírica, desde la...

Background and objective: Polycystic ovary syndrome (PCOS) is a complex metabolic disorder associated with ovulatory dysfunction, hyperandrogenism, obesity, and insulin resistance, which leads to subfertility. PCOS is the most frequent metabolic disorder in women and the major cause of infertility. Susceptibility to developing PCOS is...

Morphological embryo quality is an accurate prognostic tool for the success of assisted reproduction implantation, although complete certainty cannot be guaranteed. The transcriptome of the cumulus cells could be monitored as a faithful reflex of the physiological state of the oocytes, given the molecular crosstalk between both types of cells....