S

M

SÉMÉRIVA , M

Last name: SÉMÉRIVA

First name: M

July 1, 1996 (v1)

Journal article

Metadata-only

The tumor suppressor gene, lethal(2)giant larvae (1(2)g1), is required for cell shape change of epithelial cells during Drosophila development.

Manfruelli, P Arquier, Nathalie Hanratty, W

Inactivation of the lethal(2)giant larvae (l(2)gl) gene results in malignant transformation of imaginal disc cells and neuroblasts of the larval brain in Drosophila. Subcellular localization of the l(2)gl gene product, P127, and its biochemical characterization have indicated that it participates in the formation of the cytoskeletal network. In...

Uploaded on: December 4, 2022
June 1, 2001 (v1)

Journal article

Metadata-only

The Drosophila tumor suppressor gene lethal(2)giant larvae is required for the emission of the Decapentaplegic signal.

Arquier, Nathalie Perrin, L Manfruelli, P

The Drosophila tumor suppressor gene lethal(2) giant larvae (lgl) encodes a cytoskeletal protein required for the change in shape and polarity acquisition of epithelial cells, and also for asymmetric division of neuroblasts. We show here that lgl participates in the emission of Decapentaplegic (Dpp), a member of the transforming growth factor...

Uploaded on: December 4, 2022