SCAGLIONE , Silvia

Three-dimensional (3D) cell cultures represent fundamental tools for the comprehension of cellular phenomena both in normal and pathological conditions. In particular, mechanical stimuli not less than chemical ones have a relevant role on cell fate, cancer onset and malignant progression. Here, we realize mechanically tuned alginate hydrogels...

The development of novel 3D systems is crucial for engineering artificial tissues since the behavior of cells growth on 2D cell culture substrates does not accurately reflect that of the physiological microenvironment. In this regard, desirable 3D composites should offer tunable structural and functional properties to support appropriate...

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Three-dimensional (3D) cell cultures represent fundamental tools for the comprehension of cellular phenomena both in normal and in pathological conditions. In particular, mechanical and chemical stimuli play a relevant role on cell fate, cancer onset and malignant evolution. Here, we use mechanically-tuned alginate hydrogels to study the role...

No description

No description