SIGNORI , Alessio

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The resistance to extraction of temporary anchorage devices (TADs) depends on various factors, including miniscrew design, shear strength, and bone density. This research introduces the thread shape factor (TSF) as a new factor for the evaluation of TAD mechanical properties. The authors evaluated three TADs for a total of 27 tests:...

Randomized clinical trials (RCT) in multiple sclerosis (MS) have a recent tradition, but their number has been exponentially increasing since the first study detecting the efficacy of a disease modifying drug in MS. To examine the methodological details of reports of RCT in MS, we extracted from five leading journals all the reports of RCT...

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The assessment of the individual ability of modulating and coordinating the right and left bite force is poorly investigated. The present study describes a methodology for the assessment of the bilateral control of the biting force and evaluates the test-retest reliability in a sample of 13 healthy subjects. By modulating the intensity and the...

No subgroups of patients with higher treatment effects have been clearly detected in multiple sclerosis (MS). The aim of the present work was to evaluate whether there are subgroups of relapsing-remitting MS (RRMS) patients who are more responsive to treatments.

We prospectively compared US and MRI in patients with common fibular neuropathy.

BACKGROUND: The increasing number of effective therapies to treat multiple sclerosis (MS) raises ethical concerns for the use of placebo in clinical trials, suggesting that new clinical trial design strategies are needed. OBJECTIVES: To evaluate time to first relapse as an endpoint for MS clinical trials. METHODS: A recently-developed model...

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AIM: To study incidence and distribution of deciduous molar ankylosis. MATERIALS AND METHODS: study design: longitudinal retrospective study. A total of 512 consecutive subjects (aged 5 to 15 years) were examined at the Orthodontics and Paediatric Dentistry Department of the Genoa University School of Dentistry; for each subject an...

PURPOSE: The aim of this randomized clinical trial was to compare the potential of deproteinized bovine bone added to autologous bone or corticocancellous allograft block with or without the addition of recombinant human platelet-derived growth factor-BB (rhPDGF-BB) to regenerate mandibular atrophic ridges. MATERIALS AND METHODS: TRIAL DESIGN:...

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