SPECIALE , Andrea

Last name: SPECIALE

First name: Andrea

February 8, 2019 (v1)

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Modulazione di CD44/xCT come possibile strategia per contrastare la resistenza all'Etoposide di cellule staminali del cancro

SPECIALE, ANDREA

The current anticancer therapies for human neuroblastoma (NB) include the use of Etoposide, a drug that exerts its cytotoxic effect by inducing oxidative stress. Although the therapeutic approach with Etoposide is initially efficacious, subsequently, it selects a chemoresistant cell population which is able to adapt to the oxidative environment...

Uploaded on: March 27, 2023
2018 (v1)

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Targeting CD44/xCT is a potential strategy to sensitize human neuroblastoma stem cells to etoposide

SPECIALE, ANDREA Marengo, Barbara Traverso, Nicola

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Uploaded on: April 14, 2023
2017 (v1)

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Matrine in association with FD‑2 stimulates F508del‑cystic fibrosis transmembrane conductance regulator activity in the presence of corrector VX809

MARENGO, BARBARA SPECIALE, ANDREA Senatore, Lisa

Cystic fibrosis is caused by mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, and the predominant mutation is termed Phe508del (F508del). Therapy for F508del‑CFTR patients is based on the use of Orkambi®, a combination of VX809 and VX770. However, though Orkambi leads to an improvement in the lung function of...

Uploaded on: March 27, 2023
2017 (v1)

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Glutathione and the switch of aerobic metabolism collaborate for multi-drug resistance of neuroblastoma

DOMENICOTTI, CINZIA MARIA SPECIALE, ANDREA GARBARINO, OMBRETTA

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Uploaded on: April 14, 2023

SPECIALE , Andrea

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