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SABBADINI , Roberto

Last name: SABBADINI

First name: Roberto

2021 (v1)

Publication

Metadata-only

Probing Allosteric Hsp70 Inhibitors by Molecular Modelling Studies to Expedite the Development of Novel Combined F508del CFTR Modulators

Sabbadini, Roberto Pesce, Emanuela Parodi, Alice

Cystic fibrosis (CF) is caused by different mutations related to the cystic fibrosis transmembrane regulator protein (CFTR), with F508del being the most common. Pioneering the development of CFTR modulators, thanks to the development of effective correctors or potentiators, more recent studies deeply encouraged the administration of triple...

Uploaded on: March 27, 2023