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SAEZ , Carmen

Last name: SAEZ

First name: Carmen

March 19, 2022 (v1)

Publication

Metadata-only

Wnt/β-Catenin Signaling Contributes to Paclitaxel Resistance in Bladder Cancer Cells with Cancer Stem Cell-Like Properties

Jiménez Guerrero, Rocío Belmonte-Fernández, Alejandro Flores, M. Luz

The Wnt/β-catenin pathway plays an important role in tumor progression and chemother apy resistance and seems to be essential for the maintenance of cancer stem cells (CSC) in several tumor types. However, the interplay of these factors has not been fully addressed in bladder cancer. Here, our goal was to analyze the role of the Wnt/β-catenin...

Uploaded on: March 25, 2023
April 29, 2020 (v1)

Publication

Metadata-only

Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src.

Perez, Marco Lucena Cacace, Antonio Marín Gómez, Luis Miguel

Despite the development of new antineoplastic agents for the treatment of colorectal cancer (CRC), oxaliplatin and fluoropyrimidines remain the most commonly employed drugs for the treatment of both early and advanced disease. Intrinsic or acquired resistance is, however, an important limitation to pharmacological therapy, and the development...

Uploaded on: December 4, 2022