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SAINTIGNY , Pierre

Last name: SAINTIGNY

First name: Pierre

June 8, 2017 (v1)

Journal article

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Response to first line chemotherapy regimen is associated with efficacy of nivolumab in non-small-cell lung cancer

Kaderbhai, Courèche-Guillaume Richard, Corentin Aarnink, Anne

Nivolumab, an anti PD-1 checkpoint inhibitor has demonstrated efficacy in metastatic non-small-cell lung cancer (NSCLC) patients after failure to standard chemotherapy. Standard chemotherapy agents could promote antitumor immune response. We thus examined whether the response to first line chemotherapy could impact on nivolumab benefit. One...

Uploaded on: February 28, 2023
March 2020 (v1)

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Corrigendum to "Toll-like receptor 3 downregulation is an escape mechanism from apoptosis during hepatocarcinogenesis" [J Hepatol 71 (2019) 763–772]

Bonnin, Marc Fares, Nadim Testoni, Barbara

International audience

Uploaded on: December 4, 2022
April 9, 2021 (v1)

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Targeting netrin‐3 in small cell lung cancer and neuroblastoma

Jiang, Shan Richaud, Mathieu Vieugué, Pauline

The navigation cue netrin-1 is well-documented for its key role in cancer development and represents a promising therapeutic target currently under clinical investigation. Phase 1 and 2 clinical trials are ongoing with NP137, a humanized monoclonal antibody against netrin-1. Interestingly, the epitope recognized by NP137 in netrin-1 shares 90%...

Uploaded on: December 3, 2022