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SALEM , Naji

Last name: SALEM

First name: Naji

2015 (v1)

Publication

Metadata-only

Highly effective NK cells are associated with good prognosis in patients with metastatic prostate cancer

Pasero, Christine Gravis, Gwenaëlle Granjeaud, Samuel

Clinical outcome of patients with metastatic prostate cancer (mPC) at diagnosis is heterogeneous and unpredictable; thus alternative treatments such as immunotherapy are investigated. We retrospectively analyzed natural killer (NK) cells by flow cytometry in peripheral blood from 39 mPC patients, with 5 year-follow-up, and their correlation...

Uploaded on: April 14, 2023
2016 (v1)

Publication

Metadata-only

Inherent and tumor-driven immune tolerance in the prostate microenvironment impairs natural killer cell antitumor activity

Pasero, Christine Gravis, Gwenaëlle Guerin, Mathilde

The field of immunotherapy for solid tumors, such as prostate cancer, has been recently focusing on therapies that can counter tumor-mediated immunosuppression. Precise quantification and characterization of the immune infiltrates in tumors is crucial to improve treatment efficacy. Natural killer (NK) cells, major components of the antitumor...

Uploaded on: April 14, 2023