Prognostic scores, such as APACHE III, SAPS 3 and MPM III0, can provide estimates of the probability of death for individual patients in the ICU. However, there are controversies regarding the use of these scores for predicting outcome in patients with ARDS. Some studies have developed scores to predict mortality at bedside in this patient...
-
2016 (v1)PublicationUploaded on: April 14, 2023
-
2017 (v1)Publication
Intra-abdominal hypertension (IAH) may co-occur with the acute respiratory distress syndrome (ARDS), with significant impact on morbidity and mortality. Lung-protective controlled mechanical ventilation with low tidal volume and positive end-expiratory pressure (PEEP) has been recommended in ARDS. However, mechanical ventilation with...
Uploaded on: March 27, 2023 -
2018 (v1)Publication
Tidal volume (V T ) has been considered the main determinant of ventilator-induced lung injury (VILI). Recently, experimental studies have suggested that mechanical power transferred from the ventilator to the lungs is the promoter of VILI. We hypothesized that, as long as mechanical power is kept below a safe threshold, high V T should not be...
Uploaded on: April 14, 2023 -
2017 (v1)Publication
Lung ischemia-reperfusion injury remains a major complication after lung transplantation. Variable ventilation (VV) has been shown to improve respiratory function and reduce pulmonary histological damage compared to protective volume-controlled ventilation (VCV) in different models of lung injury induced by endotoxin, surfactant depletion by...
Uploaded on: April 14, 2023 -
2018 (v1)Publication
Background: The authors hypothesized that low tidal volume (V T ) would minimize ventilator-induced lung injury regardless of the degree of mechanical power. The authors investigated the impact of power, obtained by different combinations of V T and respiratory rate (RR), on ventilator-induced lung injury in experimental mild acute respiratory...
Uploaded on: March 27, 2023