SAVERINO D.

We have read, with great interest, articles published recently in Anatomical Sciences Education that describe histology education during the Covid-19 pandemic (Evans et al., 2020; Caruso, 2021; Cheng et al., 2021a, b; Somera et al., 2021). As histology educators at the University of Genoa, we would like to add our perspective to these conversations.

Two hundred years ago, the first of the nine volumes of Paolo Mascagni's Anatomia universa was published posthumously. This work was the fruit of a project that preoccupied Mascagni for most of his life: the Atlas of anatomy, which was the perfect replica on paper of the dissection, a fundamental part of the teaching of this discipline....

Increasing evidence shown that schizophrenia (SCZ) is associated with immunological aberrations. Particularly, microglia, the resident innate immune cells of the brain, have been implicated in SCZ pathogenesis. However, despite the abundance of empirical findings highlighting the role of microglia-mediated neuroinflammation in the...

Acute phase response (APR) following intravenous zoledronate (ZOL) administration is related to activation and increased proliferation of γδ T cells, attributed to the molecular mechanism of action of nitrogen-containing bisphosphonates (N-BPs). ZOL, however, has also been reported to inhibit the proliferation of regulatory T cells in vitro and...

Objectives: Coeliac disease is a multifactorial disorder influenced by environmental, genetic and immunological factors. Interleukin (IL)-21 has been linked to an increase disease risk and the serum level of IL-21 seems to be increased in CD compared to a healthy control population. Methods: Sera were collected from 160 CD patients, 120...

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Given the wide variety of conditioning program trainings employed, the present study compared the catabolic effects induced by CrossFit® and resistance training in moderately trained subjects. Twenty males joined either the CrossFit® group (n = 10; 30 min/day of "workout of the day") or the resistance training (RT) group (n = 10; 30 min/day of...

CTLA-4 is a key factor in regulating and maintaining self tolerance, providing a negative signal to the T cell and thus limiting immune responses. Several polymorphisms within the CTLA-4 gene have been associated with an increased risk of developing autoimmune diseases and, very recently, with susceptibility to human cancer. Acute lymphoblastic...