2000 (v1)
Publication
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Uploaded on: April 14, 2023
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1990 (v1)Publication
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Uploaded on: May 12, 2023 -
2003 (v1)Publication
OBJECTIVE: Somatostatin is an endogenous inhibitor of hormone secretion and cell proliferation. Treatment with somatostatin analogues in humans causes a reduction in size and secretory activity of endocrine tumours, including GH-secreting pituitary adenomas. This study was aimed to characterize the intracellular mechanisms mediating the in...
Uploaded on: February 4, 2024 -
1988 (v1)Publication
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Uploaded on: May 13, 2023 -
2003 (v1)Publication
BACKGROUND: Previous studies showed that the subtype 2 of somatostatin receptors (sstr2) is generally expressed by soft tissue sarcomas. MATERIALS AND METHODS: Using reverse transcription-polymerase chain reaction (RT-PCR), the present study evaluated the expression of sstr mRNA in 31 human intermediate and malignant soft tissue tumors. In 8...
Uploaded on: April 14, 2023 -
1990 (v1)Publication
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Uploaded on: May 12, 2023 -
2007 (v1)Publication
Chemokines are key factors involved in the regulation of immune response, through the activation and control of leukocyte traffic, lymphopoiesis and immune surveillance. However, a large number of chemokines and their receptors are expressed in central nervous system (CNS) cells, either constitutively or induced by inflammatory stimuli, playing...
Uploaded on: February 4, 2024 -
2003 (v1)Publication
In this paper, we describe the role of chemokine receptor CXCR4 activation by its natural ligand, the chemokine stromal cell-derived factor (SDF-1) (CXCL12), in glioblastoma cell growth in vitro. We show that both CXC chemokine receptor 4 (CXCR4) and SDF-1 mRNA are expressed in several human glioblastoma multiforme tumor tissues and in two...
Uploaded on: March 25, 2023