SCHEUERMANN , Richard H

The monkeypox virus (MPXV) outbreak confirmed in May 2022 in non-endemic countries is raising concern about the pandemic potential of novel orthopoxviruses. Little is known regarding MPXV immunity in the context of MPXV infection or vaccination with vaccinia-based vaccines (VACV). As with vaccinia, T cells are likely to provide an important...

The coronavirus (CoV) family includes several viruses infecting humans, highlighting the importance of exploring pan-CoV vaccine strategies to provide broad adaptive immune protection. We analyze T cell reac-tivity against representative Alpha (NL63) and Beta (OC43) common cold CoVs (CCCs) in pre-pandemic sam-ples. S, N, M, and nsp3 antigens...