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SCICCHITANO , Francesca

Last name: SCICCHITANO

First name: Francesca

2016 (v1)

Publication

Metadata-only

Anticonvulsive Activity in Audiogenic DBA/2 Mice of 1,4-Benzodiazepines and 1,5-Benzodiazepines with Different Activities at Cerebellar Granule Cell GABAA Receptors

GATTA, ELENA CUPELLO, AROLDO DI BRACCIO, MARIO

Herein, we tested in a model of generalized reflex epilepsy in mice different 1,4-benzodiazepines and 1,5-benzodiazepines with agonistic activity at the GABAA receptor population contributing to the peak component of the chloride current elicited by GABA in cerebellar granule cells (CGCs) in culture. The substances have all higher lipophilia...

Uploaded on: April 14, 2023