SERRANO , Aurelio

Los Progresos Recientes En Las Llamadas Ciencias Experimentales Tienen, Enmuchos Casos, Implicaciones Que Trascienden A La Propia Naturaleza Del Sabercientífico. En El Ámbito De Las Ciencias Biológicas Esto Es Particularmenteclaro Con Ciertas Disciplinas Jóvenes Como La Biología Molecular Y La Ingenieríagenética Que Han Experimentado Un...

The single-copy genes encoding putative polyphosphate–glucose phosphotransferases (PPGK, EC 2.7.1.63) from two nitrogen-fixing Cyanobacteria, Nostoc sp. PCC7120 and Nostoc punctiforme PCC73102, were cloned and functionally characterized. In contrast to their actinobacterial counterparts, the cyanobacterial PPGKs have shown the ability to...

8-Dehydrosterols are present in a wide range of biologically relevant situations, from human rare diseases to amine fungicide-treated fungi and crops. However, the molecular bases of their toxicity are still obscure. We show here that 8-dehydrosterols, but not other sterols, affect yeast vacuole acidification through V-ATPases. Moreover, erg2Δ...