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SIGNORELLO M. G.

Last name: SIGNORELLO M. G.

2020 (v1)

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Lectin-induced oxidative stress in human platelets

Signorello M. G. Ravera S. Leoncini G.

Previously we have shown that wheat germ agglutinin (WGA) and, with minor potency, Phaseolus vulgaris agglutinin (PHA), but not lens culinarian agglutinin (LCA), induce platelet aggregation, through the PLCƴ2 activation by the concerted action of src/syk and PI3K/BTK pathways. In this study, we have investigated platelet oxidative stress...

Uploaded on: April 14, 2023
2001 (v1)

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Erratum: Synthesis, antiplatelet activity and comparative molecular field analysis of substituted 2-amino-4H-pyrido[1,2-a]pyrimidin-4-ones, their congeners and isosteric analogues (Bioorganic and Medicinal Chemistry (2000) 8 (751) PII: S80968089600000109)

Roma G. Cinone N. Braccio M. D.

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Uploaded on: February 14, 2024
2021 (v1)

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New series of pyrazoles and imidazo‐pyrazoles targeting different cancer and inflammation pathways

Signorello M. G. Rapetti F. Meta E.

(1) Background: different previously synthesized pyrazoles and imidazo-pyrazoles showed interesting anti-angiogenic action, being able to interfere with ERK1/2, AKT and p38MAPK phosphorylation in different manners and with different potency; (2) Methods: here, a new small compound library, endowed with the same differently decorated chemical...

Uploaded on: April 14, 2023