SILVAIN , Christine

BACKGROUND: Ribavirin exposure after the first dose (D0AUC0-4h) \textgreater1755 mcg.h.L is predictive of sustained virological response (SVR) in patients with hepatitis C treated with peginterferon and ribavirin. The aim of this study was to test the benefit of ribavirin early dose adjustment based on this target in naive patients infected...

International audience

Importance  Prednisolone or pentoxifylline is recommended for severe alcoholic hepatitis, a life-threatening disease. The benefit of their combination is unknown. Objective  To determine whether the addition of pentoxifylline to prednisolone is more effective than prednisolone alone. Design, Setting, and Participants  Multicenter, randomized,...

Background and objectives Hepatocellular carcinoma epidemiological data are limited in France. The Epidemio Liver Immunotherapy Tecentriq outcome research (ELITor) retrospective study, based on real-world data from the Carcinome HépatocellulaIrE en France (CHIEF) French cohort of hepatocellular carcinoma patients, aimed to get insight into the...