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SINGH , Parminder

Last name: SINGH

First name: Parminder

2023 (v1)

Publication

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Safety and Activity of Immune Checkpoint Inhibitors in People Living With HIV and Cancer: A Real-World Report From the Cancer Therapy Using Checkpoint Inhibitors in People Living With HIV-International (CATCH-IT) Consortium

El Zarif, Talal Nassar, Amin H Adib, Elio

PURPOSECompared with people living without HIV (PWOH), people living with HIV (PWH) and cancer have traditionally been excluded from immune checkpoint inhibitor (ICI) trials. Furthermore, there is a paucity of real-world data on the use of ICIs in PWH and cancer.METHODSThis retrospective study included PWH treated with anti-PD-1- or...

Uploaded on: January 31, 2024
June 9, 2023 (v1)

Journal article

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Taurine deficiency as a driver of aging

Singh, Parminder Gollapalli, Kishore Mangiola, Stefano

Aging is associated with changes in circulating levels of various molecules, some of which remain undefined. We find that concentrations of circulating taurine decline with aging in mice, monkeys, and humans. A reversal of this decline through taurine supplementation increased the health span (the period of healthy living) and life span in mice...

Uploaded on: September 5, 2023