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SINGHI , Aatur

Last name: SINGHI

First name: Aatur

May 28, 2019 (v1)

Journal article

Metadata-only

Petite Integration Factor 1 (PIF1) helicase deficiency increases weight gain in Western diet-fed female mice without increased inflammatory markers or decreased glucose clearance

Belmonte, Frances Dedousis, Nikolaos Sipula, Ian

Petite Integration Factor 1 (PIF1) is a multifunctional helicase present in nuclei and mitochondria. PIF1 knock out (KO) mice exhibit accelerated weight gain and decreased wheel running on a normal chow diet. In the current study, we investigated whether Pif1 ablation alters whole body metabolism in response to weight gain. PIF1 KO and wild...

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