SINI , Valentina

Background. We evaluated the patterns of care and clinical outcomes of metastatic breast cancer patients treated with first-line trastuzumab-based therapy after previous (neo)adjuvant trastuzumab. Materials and Methods. A total of 416 consecutive, HER2-positive metastatic breast cancer patients who had received first-line trastuzumab-based...

This was a multicenter retrospective cohort study comparing the patterns of care and clinical outcomes of 416 HER2-positive metastatic breast cancer patients with de novo or recurrent disease undergoing first-line trastuzumab-based therapy. Patients with de novo disease showed significantly better survival outcomes than those with recurrent...

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