Aim: To perform a comparative epigenomic analysis of DNA methylation in spermatozoa from humans, mice, rats and mini-pigs. Materials & methods: Genome-wide DNA methylation analysis was used to compare the methylation profiles of orthologous CpG sites. Transcription profiles of early embryo development were analyzed to provide insight into the...
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November 2022 (v1)Journal articleUploaded on: November 30, 2023
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January 29, 2021 (v1)Journal article
In response to physical exercise and diet, skeletal muscle adapts to energetic demands through large transcriptional changes. This remodelling is associated with changes in skeletal muscle DNA methylation which may participate in the metabolic adaptation to extracellular stimuli. Yet, the mechanisms by which muscle-borne DNA methylation...
Uploaded on: February 27, 2023 -
March 2022 (v1)Journal article
International audience
Uploaded on: November 30, 2023 -
October 2023 (v1)Journal article
International audience
Uploaded on: November 30, 2023 -
February 2022 (v1)Journal article
International audience
Uploaded on: November 30, 2023