SOBRINO , Verónica

El cuerpo carotídeo (CC) es un pequeño órgano localizado bilateralmente en la bifurcación de la arteria carótida, y cuya principal función es la de quimiorreceptor de parámetros tan importantes como la presión parcial de oxígeno en sangre. Este órgano, que deriva de la cresta neural embrionaria y por tanto forma parte del sistema nervioso...

Oxygen constitutes a vital element for the survival of every single cell in multicellular aerobic organisms like mammals. A complex homeostatic oxygen-sensing system has evolved in these organisms, including detectors and effectors, to guarantee a proper supply of the element to every cell. The carotid body represents the most important...

The carotid body (CB), a neural-crest-derived organ and the main arterial chemoreceptor in mammals, is composed of clusters of cells called glomeruli. Each glomerulus contains neuron-like, O2-sensing glomus cells, which are innervated by sensory fibers of the petrosal ganglion and are located in close contact with a dense network of fenestrated...