2023 (v1)
Publication
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Uploaded on: July 3, 2024
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2024 (v1)Publication
Rat H9c2 cardiomyocytes overexpressing the abscisic acid (ABA) hormone receptors LANCL1 and LANCL2 have an increased mitochondrial proton gradient, respiration, and vitality after hypoxia/reoxygenation. Our aim was to investigate the role of the ABA/LANCL1-2 system in ROS turnover in H9c2 cells. H9c2 cells were retrovirally infected to induce...
Uploaded on: October 1, 2024 -
2024 (v1)PublicationIn silico exploration of LANCL2-ABA binding mode towards the identification of novel LANCL2 agonists
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Uploaded on: July 3, 2024 -
2023 (v1)Publication
The cross-kingdom stress hormone abscisic acid (ABA) and its mammalian receptors LANCL1 and LANCL2 regulate the response of cardiomyocytes to hypoxia by activating NO genera tion. The overexpression of LANCL1/2 increases transcription, phosphorylation and the activity of eNOS and improves cell vitality after hypoxia/reoxygenation via the...
Uploaded on: February 13, 2024 -
2023 (v1)Publication
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Uploaded on: February 14, 2024 -
2021 (v1)Publication
Objective: Abscisic acid (ABA) is a plant hormone also present and active in animals. In mammals, ABA regulates blood glucose levels by stimulating insulin-independent glucose uptake and metabolism in adipocytes and myocytes through its receptor LANCL2. The objective of this study was to investigate whether another member of the LANCL protein...
Uploaded on: April 14, 2023 -
2024 (v1)Publication
Background. Adipose tissue (AT) is important for energy balance, glucose and lipid homeostasis and thermogenesis. During thermogenesis, AT becomes more active and enhances oxidative metabolism. This process mainly occurs in brown AT (BAT). The promotion of this process in white AT (WAT) is called "browning" and, together with BAT activation, is...
Uploaded on: September 10, 2024 -
2023 (v1)Publication
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Uploaded on: January 31, 2024