S

J

SOO , Julia K.

Last name: SOO

First name: Julia K.

2012 (v1)

Journal article

Metadata-only

The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion

Fenouille, Nina Tichet, Mélanie Dufies, Maeva

During progression of melanoma, malignant melanocytes can be reprogrammed into mesenchymal-like cells through a process similar to epithelial-mesenchymal transition (EMT), which is associated with downregulation of the junctional protein E-cadherin and acquisition of a migratory phenotype. Recent evidence supports a role for SLUG, a...

Uploaded on: March 25, 2023