S

W

SOULEYREAU , Wilfried

Last name: SOULEYREAU

First name: Wilfried

August 25, 2022 (v1)

Journal article

Metadata-only

Practical identifiability analysis of a mechanistic model for the time to distant metastatic relapse and its application to renal cell carcinoma

Álvarez-Arenas, Arturo Souleyreau, Wilfried Emanuelli, Andrea

Distant metastasis-free survival (DMFS) curves are widely used in oncology. They are classically analyzed using the Kaplan-Meier estimator or agnostic statistical models from survival analysis. Here we report on a method to extract more information from DMFS curves using a mathematical model of primary tumor growth and metastatic dissemination....

Uploaded on: April 5, 2025
December 2021 (v1)

Journal article

Metadata-only

Experimental and computational modeling for signature and biomarker discovery of renal cell carcinoma progression

Cooley, Lindsay Rudewicz, Justine Souleyreau, Wilfried

Abstract Background Renal Cell Carcinoma (RCC) is difficult to treat with 5-year survival rate of 10% in metastatic patients. Main reasons of therapy failure are lack of validated biomarkers and scarce knowledge of the biological processes occurring during RCC progression. Thus, the investigation of mechanisms regulating RCC progression is...

Uploaded on: December 4, 2022