SPAGNOLLI , Ester

Purpose: The purpose of this study is to describe and test a modified Boussignac system for non-invasive continuous positive airway pressure, aimed at reducing the decrease in inspiratory oxygen fraction (FiO2) with higher inspiratory peak flow rates. Methods: We modified a Boussignac circuit by inserting a T-piece between the Boussignac valve...

Background: The aim of this study was to test the hypothesis that, during weaning from mechanical ventilation, when the pressure support level is reduced, oxygen consumption increases more in patients unable to sustain the decrease in ventilatory assistance (weaning failure). Methods: Patients judged eligible for weaning were enrolled. Starting...

Objective: Neutrophilic inflammation plays a key role in the pathogenesis of acute respiratory distress syndrome (ARDS) and acute lung injury (ALI). Positron emission tomography (PET) with [18F]-fluoro-2-deoxy-D- glucose (18FDG) can be used to image cellular metabolism that, during lung inflammatory processes, likely reflects neutrophils...