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SPAGNOLO , Francesco

Last name: SPAGNOLO

First name: Francesco

2016 (v1)

Publication

Metadata-only

Survival of patients with metastatic melanoma and brain metastases in the era of MAP-kinase inhibitors and immunologic checkpoint blockade antibodies: A systematic review

Spagnolo, Francesco Picasso, Virginia Lambertini, Matteo

Background: The incidence of brain metastases (BM) in melanoma patients is common and associated with poor prognosis. MAP-kinase inhibitors and immunologic checkpoint blockade antibodies led to improved survival of metastatic melanoma patients; however, patients with BM are under-represented or excluded from the majority of clinical trials and...

Uploaded on: April 14, 2023
2014 (v1)

Publication

Metadata-only

The treatment of melanoma brain metastases before the advent of targeted therapies: associations between therapeutic choice, clinical symptoms and outcome with survival

Vecchio, Stefania Spagnolo, Francesco Merlo, Domenico F

The management of melanoma brain metastases (MBM) includes different therapeutic modalities, such as surgery, radiotherapy and chemotherapy. Despite the choice of treatments, survival remains poor, exceeding 1 year only in patients with solitary metastases and absence of extracranial disease. A total of 115 consecutive MBM patients observed...

Uploaded on: April 14, 2023