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STOCCO , Gabriele

Last name: STOCCO

First name: Gabriele

February 26, 2018 (v1)

Journal article

Metadata-only

Imidazo[2,1- b ]benzothiazol Derivatives as Potential Allosteric Inhibitors of the Glucocorticoid Receptor

Christodoulou, Michael Dapiaggi, Federico Ghiringhelli, Francesca

Glucocorticoid receptor (GCR) transactivation reporter gene assays were used as an initial high-throughput screening on a diversified library of 1200 compounds for their evaluation as GCR antagonists. A class of imidazo[2,1-b]benzothiazole and imidazo[2,1-b]benzoimidazole derivatives were identified for their ability to modulate GCR...

Uploaded on: December 4, 2022