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STROH , Thomas

Last name: STROH

First name: Thomas

May 12, 2006 (v1)

Journal article

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Sustained neurotensin exposure promotes cell surface recruitment of NTS2 receptors.

Perron, Amélie Sharif, Nadder Gendron, Louis

In this study, we investigated whether persistent agonist stimulation of NTS2 receptors gives rise to down-regulation, in light of reports that their activation induced long-lasting effects. To address this issue, we incubated COS-7 cells expressing the rat NTS2 with neurotensin (NT) for up to 24 h and measured resultant cell surface [125I]-NT...

Uploaded on: February 28, 2023
May 2007 (v1)

Journal article

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Coexpression of somatostatin receptor subtype 5 affects internalization and trafficking of somatostatin receptor subtype 2.

Sharif, Nadder Gendron, Louis Wowchuk, Julia

The somatostatin [somatotropin release-inhibiting factor (SRIF)] receptor subtypes sst(2A) and sst(5) are frequently coexpressed in SRIF-responsive cells, including endocrine pituitary cells. We previously demonstrated that sst(2A) and sst(5) exhibit different subcellular localizations and regulation of cell surface expression, although they...

Uploaded on: February 28, 2023