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SUÁREZ PIZARRO , Marina

Last name: SUÁREZ PIZARRO

First name: Marina

March 10, 2022 (v1)

Publication

Metadata-only

XRCC1 Prevents Replication Fork Instability during Misincorporation of the DNA Demethylation Bases 5-Hydroxymethyl-2′-Deoxycytidine and 5-Hydroxymethyl-2′-Deoxyuridine

Peña Gómez, Mª José Suárez Pizarro, Marina Valle Rosado, Iván

Whilst avoidance of chemical modifications of DNA bases is essential to maintain genome stability, during evolution eukaryotic cells have evolved a chemically reversible modification of the cytosine base. These dynamic methylation and demethylation reactions on carbon-5 of cytosine regulate several cellular and developmental processes such as...

Uploaded on: March 25, 2023