T

A

TABERNERO , Arantxa

Last name: TABERNERO

First name: Arantxa

December 12, 2020 (v1)

Publication

Metadata-only

Connexin43 Region 266–283, via Src Inhibition, Reduces Neural Progenitor Cell Proliferation Promoted by EGF and FGF-2 and Increases Astrocytic Differentiation

Talaverón Aguilocho, Rocío Rodríguez Matarredona, Esperanza Herrera Lira, Alejandro

Neural progenitor cells (NPCs) are self-renewing cells that give rise to the major cells in the nervous system and are considered to be the possible cell of origin of glioblastoma. The gap junction protein connexin43 (Cx43) is expressed by NPCs, exerting channel-dependent and -independent roles. We focused on one property of Cx43—its ability to...

Uploaded on: December 4, 2022
August 18, 2023 (v1)

Publication

Metadata-only

Antiproliferative effect of boldine on neural progenitor cells and on glioblastoma cells

Jiménez Madrona, Enrique Morado Díaz, Camilo José Talaverón Aguilocho, Rocío

The subventricular zone (SVZ) is a brain region that contains neural stem cells and progenitor cells (NSCs/NPCs) from which new neurons and glial cells are formed during adulthood in mammals. Recent data indicate that SVZ NSCs are the cell type that acquires the initial tumorigenic mutation in glioblastoma (GBM), the most aggressive form of...

Uploaded on: October 11, 2023