TAPIO ALA NISSILA

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Despite the widespread use of triangular nanochannels for the manipulation and analysis of DNA, studies on the confining effects induced by these nanofluidic structures on the molecules are still absent. Here, we perform coarse-grained Monte Carlo simulations to study the conformations of DNA in nanochannels. The influence of the shape of the...

There is currently a growing interest in control of stretching of DNA inside nanoconfined regions due to the possibility to analyze and manipulate single biomolecules for applications such as DNA mapping and barcoding, which are based on stretching the DNA in a linear fashion. In the present work, we couple Finite Element Methods and Monte...

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