T

G

THOMAS , Gavin H.

Last name: THOMAS

First name: Gavin H.

December 14, 2020 (v1)

Publication

Metadata-only

Uncovering a novel molecular mechanism for scavenging sialic acids in bacteria

Bell, Andrew Severi, Emmanuele Lee, Micah

The human gut symbiont Ruminococcus gnavus scavenges host-derived N-acetylneuraminic acid (Neu5Ac) from mucins by converting it to 2,7-anhydro-Neu5Ac. We previously showed that 2,7-anhydro-Neu5Ac is transported into R. gnavus ATCC 29149 before being converted back to Neu5Ac for further metabolic processing. However, the molecular mechanism...

Uploaded on: December 4, 2022