T

M

TORRES , Magda-Liz

Last name: TORRES

First name: Magda-Liz

2015 (v1)

Publication

Metadata-only

Deletion of WASp and N-WASp in B cells cripples the germinal center response and results in production of IgM autoantibodies

Dahlberg, Carin I. M. Torres, Magda-Liz Petersen, Sven H.

Humoral immunodeficiency caused by mutations in the Wiskott-Aldrich syndrome protein (WASp) is associated with failure to respond to common pathogens and high frequency of autoimmunity. Here we addressed the question how deficiency in WASp and the homologous protein N-WASp skews the immune response towards autoreactivity. Mice devoid of WASp or...

Uploaded on: April 14, 2023